MDS company's all-digital servo control blister packaging machine

The blister packs of pharmaceuticals are increasingly welcomed by pharmaceutical companies and consumers due to their long storage period, convenient carrying and low cost, and they have become the mainstream packaging of solid pharmaceuticals.

MediSeal GmbH is a manufacturer specializing in the production of pharmaceutical packaging equipment. It has a history of producing blister packs, four-side sealed pouches and cartoning production lines for over 70 years. The design and manufacture of equipment meet the requirements of the current GMP requirements for pharmaceutical production. . Among them, the company's all-digital servo control blister packaging technology has been highly rated by the industry. Madison full digital servo control technology uses 112400 axis coded precise positioning. Through the bubble-grating detection device, the machine can automatically identify the position deviation of the bubble (the measurement control accuracy is within 0.01mm), and feedback the change amount to the PLC. The controllers and controllers will automatically perform real-time corrections accordingly so as to ensure the precise position of each blister card at each workstation on the entire line. Based on the full-line full-digital servo control, the production line pays more attention to continuously improving the details of each link, and ensures that the production and the products have excellent quality on the basis of high efficiency.

Film forming process carefully "care"

In the forming station, a buffer zone is generally designed between the film roll release and the film heating area. The conventional method (shown in FIG. 1) uses a film feed roller and an angle swing bar to control the transport film into the heating area, although This dynamic balance method is sufficient to satisfy the film supply during continuous operation of the device, but in any case there must be a certain tension between the pendulum swinging and the film feeding roller, and the friction between the pendulum rod and the film will generate electrostatic adsorption force. , This affects the feeding of the film feeding roller to the film, resulting in interference with the external force and affecting the quality of the blister during film heating and forming. In order to eliminate external interference, Medici's blister packaging machine uses an ultrasonic sensor instead of the angle pendulum (shown in Figure 2). A certain amount of film is suspended in its own weight between the film feeding roller and film roll release. The amount of suspension can be controlled by an ultrasonic sensor, and the film is fed to the heating forming area by the film feeding roller without any external force interference. When the ultrasonic sensor detects the rise of the hanging film position, the film roll is quickly released to supplement the film. The membrane's suspension reserves ensure the formation quality of the blister.

After the blister is formed, the forming mold is generally opened, and the formed film is separated from the forming mold by its own tension. In this way, the formed film cannot be completely separated from the forming mold when the physical and chemical properties of the film are changed. When the film is pulled, the formed bubble tends to be scratched and damaged by the forming mold. In order to ensure the blister stripping reliability, Medisil uses a vacuum stripping device. The vacuum generation time can be adjusted according to different membranes. When the forming mold is opened, the vacuum controlled by the electronic cam is also opened at the same time, and the formed film and the mold are naturally separated under the combined action of tension and vacuum to prevent the blisters from being scratched.

The high-temperature preheated film and the formed blisters should be said to be in an immature state. Through these details, Medici realized that the preheated film and the formed blisters are free from external interference. During the entire heating and forming process, the film has been Carefully "care" into the next area.

Sealing pressure "catty"

The air tightness of blister packs is the focus of quality control, controlled by the pressure of the seal and the temperature of the seal. However, the pressure and temperature requirements of different packaging materials are often different. Conventional equipment generally increases the airtightness of the blister board by adjusting the sealing temperature, because the sealing pressure for each time in the production process cannot be known. Causes an excessively high sealing temperature and destroys the drug in the blister, especially some lyophilized products that are very sensitive to temperature. Taking this into account, Medcy installed a pressure sensor and displayed the pressure of each seal on the control panel by means of analog-to-digital conversion. The accuracy can reach 0.1 KN. At the same time, the upper and lower limits of the sealing pressure are set, when the sealing pressure Outside of the set range, these sealed blister packs will be rejected. In this way, the sealing pressure of the sealing station can be controlled within a certain range, depending on the optimum combination of pressure and temperature of the different packaging materials.

Punching classification "each in its place"

There are two types of blisters scrap board: empty board and underfill board. In the general production workshop, the lack of board needs to be recycled, so Medisis designed a separate collection device for the empty board and the missing board. The empty board and the missing board. The guide plates enter the respective recovery boxes, respectively, and the punched waste edges can be directly entered into the waste side boxes, so that the punched and cut objects are in their respective positions, eliminating the time spent on classifying these reject items. Moreover, when the empty board and the missing board pass through the guide board, there is a sensor to check and confirm that the waste board has been removed, so as to prevent the waste board from being brought into the qualified product at the time of high-speed production. In addition, although Medici's blister machines have a high yield, a level sensor is installed on the top of the recovery box. When the reject is filled with the recovery box or waste edge box, the machine will automatically warn the operator Need to remove the box out of the items.

Die change "embedded" into the hearts of people

The biggest advantage of digital servo is the quick and convenient replacement of molds. The specifications of different products include: all specifications, the lengths of the drawing stations for forming stations, sealing stations, and punching stations, the parameters for the camera detection system, and the data for the elimination of scrap plates. All are stored in the computer, eliminating the operator's time for re-adjustment of specifications - the operator simply calls the corresponding product specification program, and all specification parameters can be automatically recalled from the memory in the machine. At the same time, each station's molds such as forming molds, sealing molds, punching molds, and guide rails are also simple and convenient to replace. Each part is equipped with a special quick locking system for Medicsi, as long as each mold is embedded in the positioning hole or guide groove of the base, and then It is sufficient to lock the respective quick-locking parts. This kind of replacement is accurate and quick without special tools.

Remote troubleshooting "Global synchronization"

A modem is configured in the main control cabinet of all Medicilon equipments. When the equipment is accepted, it is necessary to test whether the connection from the German headquarters can be connected with the modem to ensure remote fault diagnosis. In this way, once the equipment has a problem in the program, regardless of the location of the equipment on the earth, through the remote fault diagnosis system, the operating parameters of the equipment can be directly displayed on the diagnostic platform of the Medici Germany factory and data can be entered by entering the advanced password authority. modify. The application of a new generation of digital servo technology is more conducive to remote fault diagnosis. This technology can also realize remote diagnosis of a single servo motor. Engineers can even find the serial number and fault code of the servo motor. Therefore, for the sudden stoppage of failures, this globally synchronized remote diagnosis technology enables the production site to find the cause of the failure in the shortest possible time, reducing unnecessary delays.

Quality Control "Conviction"

In recent years, the safety of pharmaceutical packaging has been placed in a prominent position. Many pharmaceutical equipment suppliers have paid special attention to testing equipment. However, on-line testing equipment is generally provided by professional testing equipment manufacturers, such as bubble eyelets. Detection, lack of filling board detection, etc., when the device detects a problem, the device will send a signal to the PLC to remove the corresponding blister board, but in this way, there will be blind spots in the entire line of control, such as detecting the external interference of the device or Blister board is just at a zero point. In response to this situation, Medici adopted a set-up to consider that every blister card was problematic from the outset, and then passed a qualified confirmation value for each detection device, only when all tests passed the qualified value. The final confirmation of a qualified product avoids blind spots in the entire line control.

In the era of continuous upgrading of the pharmaceutical industry and the emergence of new technologies, the focus on all details has made Medisix’s all-digital servo-controlled packaging machinery the most dazzling star in the field of blister packaging.

Source: Packaging Machinery