Determination of amikacin sulfate by ion chromatography pulsed amperometry

Amikacin sulfate is an aminoglycoside antibiotic that has a good effect on most Enterobacteriaceae bacteria. The Chinese Pharmacopoeia uses thin layer chromatography, the American Pharmacopoeia uses anion exchange chromatography, and uses the same separation mechanism and reverse phase as the European Pharmacopoeia. Liquid chromatography separates target substances and related impurities, and improves the electrochemical detection cell to obtain better separation and detection.

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